The first years of school are critical in establishing a foundation for positive long-term academic, social and well-being outcomes. Mindfulness-based interventions may help students transition well into school, but few robust studies have been conducted in this age group.
We aim to determine whether compared with controls, children who receive a mindfulness intervention within the first years of primary school have better: (1) immediate attention/short-term memory at 18 months post-randomisation (primary outcome); (2) inhibition, working memory and cognitive flexibility at 18 months post-randomisation; (3) socio-emotional well-being, emotion-regulation and mental health-related behaviours at 6 and 18 months post-randomisation; (4) sustained changes in teacher practice and classroom interactions at 18 months post-randomisation.
Furthermore, we aim to determine whether the implementation predicts the efficacy of the intervention, and the cost effectiveness relative to outcomes.This cluster randomised controlled trial will be conducted in 22 primary schools in disadvantaged areas of Melbourne, Australia. 826 students in the first year of primary school will be recruited to detect between groups differences of Cohen’s d=0.25 at the 18-month follow-up.
Parent, teacher and child-assessment measures of child attention, emotion-regulation, executive functioning, socio-emotional well-being, mental health-related behaviour and learning, parent mental well-being, teacher well-being will be collected 6 and 18 months post-randomisation.
NOP56 Ribonucleoprotein (NOP56) Antibody |
abx235795-100ug |
Abbexa |
100 ug |
EUR 509 |
- Shipped within 5-12 working days.
|
Nop56 Ribonucleoprotein Homolog (Yeast) (NOP56) Antibody |
20-abx114153 |
Abbexa |
|
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- Shipped within 5-10 working days.
|
Human NOP56 Ribonucleoprotein (NOP56) ELISA Kit |
abx381849-96tests |
Abbexa |
96 tests |
EUR 911 |
- Shipped within 5-12 working days.
|
NOP56 siRNA |
20-abx926151 |
Abbexa |
|
|
- Shipped within 5-10 working days.
|
NOP56 siRNA |
20-abx926152 |
Abbexa |
|
|
- Shipped within 5-10 working days.
|
NOP56 antibody |
70R-18923 |
Fitzgerald |
50 ul |
EUR 435 |
Description: Rabbit polyclonal NOP56 antibody |
NOP56 Antibody |
1-CSB-PA384993 |
Cusabio |
|
|
- Form: Liquid
- Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Description: A polyclonal antibody against NOP56. Recognizes NOP56 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1:500-2000, ELISA:1:10000-20000 |
NOP56 Antibody |
1-CSB-PA015939GA01HU |
Cusabio |
|
|
- Form: Liquid
- Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20℃, Avoid freeze / thaw cycles. Antigen Affinity purified
|
Description: A polyclonal antibody against NOP56. Recognizes NOP56 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB |
NOP56 Polyclonal Antibody |
ES8503-100ul |
ELK Biotech |
100ul |
EUR 279 |
Description: A Rabbit Polyclonal antibody against NOP56 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
NOP56 Polyclonal Antibody |
ES8503-50ul |
ELK Biotech |
50ul |
EUR 207 |
Description: A Rabbit Polyclonal antibody against NOP56 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
anti- NOP56 antibody |
FNab05795 |
FN Test |
100µg |
EUR 548.75 |
- Immunogen: NOP56 ribonucleoprotein homolog(yeast)
- Uniprot ID: O00567
- Gene ID: 10528
- Research Area: Neuroscience, Metabolism, Epigenetics
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Description: Antibody raised against NOP56 |
NOP56 Polyclonal Antibody |
ABP57510-003ml |
Abbkine |
0.03ml |
EUR 158 |
- Immunogen information: Synthesized peptide derived from NOP56 at AA range: 191-240
- Applications tips:
|
Description: A polyclonal antibody for detection of NOP56 from Human, Mouse, Rat. This NOP56 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from NOP56 at AA range: 191-240 |
NOP56 Polyclonal Antibody |
ABP57510-01ml |
Abbkine |
0.1ml |
EUR 289 |
- Immunogen information: Synthesized peptide derived from NOP56 at AA range: 191-240
- Applications tips:
|
Description: A polyclonal antibody for detection of NOP56 from Human, Mouse, Rat. This NOP56 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from NOP56 at AA range: 191-240 |
NOP56 Polyclonal Antibody |
ABP57510-02ml |
Abbkine |
0.2ml |
EUR 414 |
- Immunogen information: Synthesized peptide derived from NOP56 at AA range: 191-240
- Applications tips:
|
Description: A polyclonal antibody for detection of NOP56 from Human, Mouse, Rat. This NOP56 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from NOP56 at AA range: 191-240 |
Anti-NOP56 Antibody |
A04335 |
BosterBio |
100ul |
EUR 397 |
Description: Rabbit Polyclonal Antibody for NOP56 Antibody (NOP56) detection.tested for IHC, WB in Human, Mouse, Rat. |
NOP56 Rabbit pAb |
A8040-100ul |
Abclonal |
100 ul |
EUR 384 |
NOP56 Rabbit pAb |
A8040-200ul |
Abclonal |
200 ul |
Ask for price |
NOP56 Rabbit pAb |
A8040-20ul |
Abclonal |
20 ul |
Ask for price |
NOP56 Rabbit pAb |
A8040-50ul |
Abclonal |
50 ul |
EUR 265 |
NOP56 Polyclonal Antibody |
46736-100ul |
SAB |
100ul |
EUR 252 |
NOP56 Polyclonal Antibody |
46736-50ul |
SAB |
50ul |
EUR 187 |
Anti-NOP56 antibody |
STJ98616 |
St John's Laboratory |
200 µl |
EUR 197 |
Description: Rabbit polyclonal to NOP56. |
Anti-NOP56 antibody |
STJ110344 |
St John's Laboratory |
100 µl |
EUR 393 |
Description: Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. |
Mouse NOP56 shRNA Plasmid |
20-abx975991 |
Abbexa |
|
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- Shipped within 15-20 working days.
|
Human NOP56 shRNA Plasmid |
20-abx957155 |
Abbexa |
|
|
- Shipped within 15-20 working days.
|
NOP56 Recombinant Protein (Human) |
RP021469 |
ABM |
100 ug |
Ask for price |
NOP56 Recombinant Protein (Rat) |
RP214226 |
ABM |
100 ug |
Ask for price |
NOP56 Recombinant Protein (Mouse) |
RP154574 |
ABM |
100 ug |
Ask for price |
NOP56 ORF Vector (Human) (pORF) |
ORF007157 |
ABM |
1.0 ug DNA |
EUR 95 |
Nop56 ORF Vector (Rat) (pORF) |
ORF071410 |
ABM |
1.0 ug DNA |
EUR 506 |
Nop56 ORF Vector (Mouse) (pORF) |
ORF051526 |
ABM |
1.0 ug DNA |
EUR 506 |
NOP56 sgRNA CRISPR Lentivector set (Human) |
K1440801 |
ABM |
3 x 1.0 ug |
EUR 339 |
Nop56 sgRNA CRISPR Lentivector set (Mouse) |
K4919601 |
ABM |
3 x 1.0 ug |
EUR 339 |
Nop56 sgRNA CRISPR Lentivector set (Rat) |
K7169201 |
ABM |
3 x 1.0 ug |
EUR 339 |
Bovine Nucleolar protein 56, NOP56 ELISA KIT |
ELI-16702b |
Lifescience Market |
96 Tests |
EUR 928 |
Human Nucleolar protein 56, NOP56 ELISA KIT |
ELI-35313h |
Lifescience Market |
96 Tests |
EUR 824 |
Mouse Nucleolar protein 56, Nop56 ELISA KIT |
ELI-46118m |
Lifescience Market |
96 Tests |
EUR 865 |
NOP56 sgRNA CRISPR Lentivector (Human) (Target 1) |
K1440802 |
ABM |
1.0 ug DNA |
EUR 154 |
NOP56 sgRNA CRISPR Lentivector (Human) (Target 2) |
K1440803 |
ABM |
1.0 ug DNA |
EUR 154 |
NOP56 sgRNA CRISPR Lentivector (Human) (Target 3) |
K1440804 |
ABM |
1.0 ug DNA |
EUR 154 |
Nop56 sgRNA CRISPR Lentivector (Mouse) (Target 1) |
K4919602 |
ABM |
1.0 ug DNA |
EUR 154 |
Nop56 sgRNA CRISPR Lentivector (Mouse) (Target 2) |
K4919603 |
ABM |
1.0 ug DNA |
EUR 154 |
Nop56 sgRNA CRISPR Lentivector (Mouse) (Target 3) |
K4919604 |
ABM |
1.0 ug DNA |
EUR 154 |
Nop56 sgRNA CRISPR Lentivector (Rat) (Target 1) |
K7169202 |
ABM |
1.0 ug DNA |
EUR 154 |
Nop56 sgRNA CRISPR Lentivector (Rat) (Target 2) |
K7169203 |
ABM |
1.0 ug DNA |
EUR 154 |
Nop56 sgRNA CRISPR Lentivector (Rat) (Target 3) |
K7169204 |
ABM |
1.0 ug DNA |
EUR 154 |
NOP56 Protein Vector (Human) (pPB-C-His) |
PV028625 |
ABM |
500 ng |
EUR 329 |
NOP56 Protein Vector (Human) (pPB-N-His) |
PV028626 |
ABM |
500 ng |
EUR 329 |
NOP56 Protein Vector (Human) (pPM-C-HA) |
PV028627 |
ABM |
500 ng |
EUR 329 |
NOP56 Protein Vector (Human) (pPM-C-His) |
PV028628 |
ABM |
500 ng |
EUR 329 |
NOP56 Protein Vector (Mouse) (pPB-C-His) |
PV206102 |
ABM |
500 ng |
EUR 603 |
NOP56 Protein Vector (Mouse) (pPB-N-His) |
PV206103 |
ABM |
500 ng |
EUR 603 |
NOP56 Protein Vector (Mouse) (pPM-C-HA) |
PV206104 |
ABM |
500 ng |
EUR 603 |
NOP56 Protein Vector (Mouse) (pPM-C-His) |
PV206105 |
ABM |
500 ng |
EUR 603 |
NOP56 Protein Vector (Rat) (pPB-C-His) |
PV285638 |
ABM |
500 ng |
EUR 603 |
NOP56 Protein Vector (Rat) (pPB-N-His) |
PV285639 |
ABM |
500 ng |
EUR 603 |
NOP56 Protein Vector (Rat) (pPM-C-HA) |
PV285640 |
ABM |
500 ng |
EUR 603 |
NOP56 Protein Vector (Rat) (pPM-C-His) |
PV285641 |
ABM |
500 ng |
EUR 603 |
Nop56 3'UTR GFP Stable Cell Line |
TU164211 |
ABM |
1.0 ml |
Ask for price |
NOP56 3'UTR Luciferase Stable Cell Line |
TU015823 |
ABM |
1.0 ml |
EUR 1394 |
Nop56 3'UTR Luciferase Stable Cell Line |
TU114211 |
ABM |
1.0 ml |
Ask for price |
NOP56 3'UTR GFP Stable Cell Line |
TU065823 |
ABM |
1.0 ml |
EUR 1394 |
Nop56 3'UTR GFP Stable Cell Line |
TU264084 |
ABM |
1.0 ml |
Ask for price |
Nop56 3'UTR Luciferase Stable Cell Line |
TU214084 |
ABM |
1.0 ml |
Ask for price |
NOP56 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV) |
LV628063 |
ABM |
1.0 ug DNA |
EUR 682 |
NOP56 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC) |
LV628067 |
ABM |
1.0 ug DNA |
EUR 682 |
NOP56 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a) |
LV628068 |
ABM |
1.0 ug DNA |
EUR 682 |
NOP56 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC) |
LV792199 |
ABM |
1.0 ug DNA |
EUR 316 |
NOP56 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a) |
LV792200 |
ABM |
1.0 ug DNA |
EUR 316 |
NOP56 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human) |
K1440805 |
ABM |
3 x 1.0 ug |
EUR 376 |
Nop56 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse) |
K4919605 |
ABM |
3 x 1.0 ug |
EUR 376 |
Nop56 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat) |
K7169205 |
ABM |
3 x 1.0 ug |
EUR 376 |
NOP56 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1) |
K1440806 |
ABM |
1.0 ug DNA |
EUR 167 |
NOP56 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2) |
K1440807 |
ABM |
1.0 ug DNA |
EUR 167 |
NOP56 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3) |
K1440808 |
ABM |
1.0 ug DNA |
EUR 167 |
Nop56 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1) |
K4919606 |
ABM |
1.0 ug DNA |
EUR 167 |
Nop56 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2) |
K4919607 |
ABM |
1.0 ug DNA |
EUR 167 |
Nop56 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3) |
K4919608 |
ABM |
1.0 ug DNA |
EUR 167 |
NOP56 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA) |
LV628064 |
ABM |
1.0 ug DNA |
EUR 682 |
NOP56 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro) |
LV628065 |
ABM |
1.0 ug DNA |
EUR 740 |
NOP56 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro) |
LV628066 |
ABM |
1.0 ug DNA |
EUR 740 |
Nop56 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1) |
K7169206 |
ABM |
1.0 ug DNA |
EUR 167 |
Nop56 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2) |
K7169207 |
ABM |
1.0 ug DNA |
EUR 167 |
Nop56 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3) |
K7169208 |
ABM |
1.0 ug DNA |
EUR 167 |
Implementation factors will be measured throughout the study. Intention-to-treat analyses, accounting for clustering within schools and classes, will adopt a two-level random effects linear regression model to examine outcomes for the intervention versus control students. Unadjusted and analyses adjusted for baseline scores, baseline age, gender and family socioeconomic status will be conducted.
Ethics approval has been received by the Human Research Ethics Committee at the University of Melbourne. Findings will be reported in peer-review publications, national and international conference presentations and research snapshots directly provided to participating schools and families.