Background: Brain radiotherapy is the usual remedy possibility for a number of mind metastases (BMs) from non-small cell lung most cancers (NSCLC), particularly in the absence of a driver mutation. However, the prognosis for such sufferers stays poor. Apatinib is a potent antiangiogenic compound directed on the vascular endothelial progress issue receptor-2 (VEGFR-2); nevertheless, to date, there are not any investigations of apatinib concurrent with mind radiotherapy for NSCLC sufferers with BMs.
We report a case of EGFR wild-type and ALK-negative lung adenocarcinoma affected person with a number of symptomatic BMs, who obtained apatinib along with mind radiation remedy. A positive oncologic consequence was achieved for each mind metastatic lesions and the first pulmonary tumor. Case Presentation: A 61-year-old feminine (by no means smoker) who initially offered with headache and dizziness was recognized with lung adenocarcinoma with a number of mind metastasis (cT2aN3M1b stage IV), and was unfavorable for EGFR and ALK.
The affected person refused to obtain chemotherapy and was solely amenable to mind radiotherapy and focused remedy. After approval from the institutional ethics committee, she underwent concurrent oral apatinib (500 mg/day) with complete mind radiation remedy (WBRT) (37.5Gy) with simultaneous in-field increase (49.5Gy) in 15 fractions with picture guided intensity-modulated radiotherapy.
Three weeks later, neurologic signs totally ceased and a partial response (PR) for the BMs with near-complete decision of peritumoral mind edema was achieved. Chest CT carried out on the identical time and confirmed shrinkage of the lung main with a PR.
The affected person suffered grade III oral mucositis one week after mind radiotherapy and refused additional apatinib. At 12 months after mind radiotherapy, the mind tumors remained properly managed. Conclusions: This is the primary identified documentation of a speedy medical response of apatinib concurrent with mind radiotherapy in a lung adenocarcinoma affected person with symptomatic a number of BMs. Apatinib mixed with mind radiotherapy could possibly be another remedy possibility for BMs from NSCLC, particularly for these with no driver mutation. Further medical trials are required to corroborate this discovery.
Pattern of Pediatric Supracondylar Fracture Operated at A Rural Teaching Hospital of Nepal: A Descriptive Cross-sectional Study.
Supracondylar fracture of humerus is likely one of the frequent pediatric fractures encountered in our every day medical observe. The goal of this examine is to decide the sample of supracondylar fracture operated at rural educating hospital of Jumla, Karnali Nepal.A descriptive cross sectional examine was carried out at Jumla, Karnali after Institutional Review Committee approval.
Operating room notes from 15 May 2017 to 16 November 2019 had been retrieved to collect the next data: sufferers tackle, age, intercourse, aspect, harm mechanism, displacement, neurovascular harm, concurrent accidents, preliminary administration by conventional bone setters, time between harm and surgical procedure, operative method.
CARD15/NOD2 |
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| MBS8577235-01mLAF405S | MyBiosource | 0.1mL(AF405S) | 565 EUR |
CARD15/NOD2 |
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| MBS8577235-01mLAF610 | MyBiosource | 0.1mL(AF610) | 565 EUR |
CARD15/NOD2 |
|||
| MBS8577235-01mLAF635 | MyBiosource | 0.1mL(AF635) | 565 EUR |
NOD2 Peptide |
|||
| 2511P | ProSci | 0.05 mg | 197.7 EUR |
|
Description: (NT) NOD2 peptide |
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NOD2 Peptide |
|||
| 2513P | ProSci | 0.05 mg | 197.7 EUR |
|
Description: (CT) NOD2 peptide |
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NOD2 Peptide |
|||
| 45-973P | ProSci | 0.1 mg | 405.6 EUR |
|
Description: (IN) CARD15 / NOD2 Peptide |
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NOD2 Peptide |
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| MBS151914-005mg | MyBiosource | 0.05mg | 175 EUR |
NOD2 Peptide |
|||
| MBS151914-5x005mg | MyBiosource | 5x0.05mg | 770 EUR |
NOD2 Peptide |
|||
| MBS152977-005mg | MyBiosource | 0.05mg | 175 EUR |
NOD2 Peptide |
|||
| MBS152977-5x005mg | MyBiosource | 5x0.05mg | 770 EUR |
Nod2 antibody |
|||
| 10R-6553 | Fitzgerald | 100 ug | 218 EUR |
|
Description: Rat monoclonal Nod2 antibody |
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NOD2 Antibody |
|||
| 24158 | SAB | 100ul | 479 EUR |
NOD2 Antibody |
|||
| 24158-100ul | SAB | 100ul | 468 EUR |
NOD2 Antibody |
|||
| 24159 | SAB | 100ul | 479 EUR |
NOD2 Antibody |
|||
| 24159-100ul | SAB | 100ul | 468 EUR |
NOD2 Antibody |
|||
| 2511-002mg | ProSci | 0.02 mg | 206.18 EUR |
|
Description: NOD2 Antibody: Apaf-1 and NOD1 are members of a new family, which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2. NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-κB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease that is a main type of chronic inflammatory bowel disease. |
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NOD2 Antibody |
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| 2511-01mg | ProSci | 0.1 mg | 523.7 EUR |
|
Description: NOD2 Antibody: Apaf-1 and NOD1 are members of a new family, which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2. NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-κB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease that is a main type of chronic inflammatory bowel disease. |
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NOD2 Antibody |
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| 2513-002mg | ProSci | 0.02 mg | 206.18 EUR |
|
Description: NOD2 Antibody: Apaf-1 and NOD1 are members of a new family, which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2. NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-κB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease that is a main type of chronic inflammatory bowel disease. |
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NOD2 Antibody |
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| 2513-01mg | ProSci | 0.1 mg | 523.7 EUR |
|
Description: NOD2 Antibody: Apaf-1 and NOD1 are members of a new family, which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2. NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-κB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease that is a main type of chronic inflammatory bowel disease. |
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NOD2 Antibody |
|||
| 37460 | SAB | 100ul | 319 EUR |
NOD2 Antibody |
|||
| 37460-100ul | SAB | 100ul | 302.4 EUR |
NOD2 Antibody |
|||
| 1-CSB-PA876985 | Cusabio |
|
|
|
Description: A polyclonal antibody against NOD2. Recognizes NOD2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100 |
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NOD2 Antibody |
|||
| 1-CSB-PA881021LA01HU | Cusabio |
|
|
|
Description: A polyclonal antibody against NOD2. Recognizes NOD2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 |
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NOD2 Antibody |
|||
| E037460 | EnoGene | 100μg/100μl | 255 EUR |
|
Description: Available in various conjugation types. |
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NOD2 Antibody |
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| 1-CSB-PA015915GA01HU | Cusabio |
|
|
|
Description: A polyclonal antibody against NOD2. Recognizes NOD2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB |
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NOD2 Antibody |
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| DF12125 | Affbiotech | 200ul | 420 EUR |
NOD2 Antibody |
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| DF12125-100ul | Affinity Biosciences | 100ul | 280 EUR |
NOD2 Antibody |
|||
| DF12125-200ul | Affinity Biosciences | 200ul | 350 EUR |
NOD2 Antibody |
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| E91323 | EnoGene | 100ul | 255 EUR |
|
Description: Available in various conjugation types. |
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NOD2 antibody |
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| 70R-18913 | Fitzgerald | 50 ul | 289 EUR |
|
Description: Rabbit polyclonal NOD2 antibody |
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NOD2 Antibody |
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| 1-CSB-PA446192 | Cusabio |
|
|
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Description: A polyclonal antibody against NOD2. Recognizes NOD2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200 |
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NOD2 Antibody |
|||
| R34436-100UG | NSJ Bioreagents | 100 ug | 339.15 EUR |
|
Description: Additional name(s) for this target protein: Nucleotide-binding oligomerization domain-containing protein 2, caspase recruitment domain family, member 15; CARD15 |
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NOD2 Antibody |
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| MBS7128669-005mL | MyBiosource | 0.05mL | 190 EUR |
NOD2 Antibody |
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| MBS7128669-01mL | MyBiosource | 0.1mL | 270 EUR |
NOD2 Antibody |
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| MBS7128669-5x01mL | MyBiosource | 5x0.1mL | 1205 EUR |
NOD2 Antibody |
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| MBS7128670-005mL | MyBiosource | 0.05mL | 190 EUR |
NOD2 Antibody |
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| MBS7128670-01mL | MyBiosource | 0.1mL | 270 EUR |
NOD2 Antibody |
|||
| MBS7128670-5x01mL | MyBiosource | 5x0.1mL | 1205 EUR |
NOD2 Antibody |
|||
| MBS7051336-005mg | MyBiosource | 0.05mg | 190 EUR |
NOD2 Antibody |
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| MBS7051336-01mg | MyBiosource | 0.1mg | 270 EUR |
NOD2 Antibody |
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| MBS7051336-5x01mg | MyBiosource | 5x0.1mg | 1205 EUR |
NOD2 Antibody |
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| MBS9408700-01mL | MyBiosource | 0.1mL | 495 EUR |
NOD2 Antibody |
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| MBS9408700-5x01mL | MyBiosource | 5x0.1mL | 2075 EUR |
NOD2 Antibody |
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| MBS9412342-01mL | MyBiosource | 0.1mL | 495 EUR |
NOD2 Antibody |
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| MBS9412342-5x01mL | MyBiosource | 5x0.1mL | 2075 EUR |
NOD2 Antibody |
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| MBS9403964-01mL | MyBiosource | 0.1mL | 305 EUR |
NOD2 Antibody |
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| MBS9403964-5x01mL | MyBiosource | 5x0.1mL | 1230 EUR |
NOD2 Antibody |
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| MBS8504992-01mL | MyBiosource | 0.1mL | 325 EUR |
NOD2 Antibody |
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| MBS8504992-01mLAF405L | MyBiosource | 0.1mL(AF405L) | 565 EUR |
NOD2 Antibody |
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| MBS8504992-01mLAF405S | MyBiosource | 0.1mL(AF405S) | 565 EUR |
NOD2 Antibody |
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| MBS8504992-01mLAF610 | MyBiosource | 0.1mL(AF610) | 565 EUR |
NOD2 Antibody |
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| MBS8504992-01mLAF635 | MyBiosource | 0.1mL(AF635) | 565 EUR |
Nod2 antibody |
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| MBS838497-005mg | MyBiosource | 0.05mg | 390 EUR |
Nod2 antibody |
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| MBS838497-01mg | MyBiosource | 0.1mg | 1175 EUR |
Nod2 antibody |
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| MBS838497-5x01mg | MyBiosource | 5x0.1mg | 5145 EUR |
NOD2 Antibody |
|||
| MBS150770-01mg | MyBiosource | 0.1mg | 445 EUR |
NOD2 Antibody |
|||
| MBS150770-5x01mg | MyBiosource | 5x0.1mg | 1965 EUR |
NOD2 Antibody |
|||
| MBS150816-01mg | MyBiosource | 0.1mg | 445 EUR |
NOD2 Antibody |
|||
| MBS150816-5x01mg | MyBiosource | 5x0.1mg | 1965 EUR |
NOD2 Antibody |
|||
| MBS9603353-01mL | MyBiosource | 0.1mL | 260 EUR |
NOD2 Antibody |
|||
| MBS9603353-02mL | MyBiosource | 0.2mL | 305 EUR |
NOD2 Antibody |
|||
| MBS9603353-5x02mL | MyBiosource | 5x0.2mL | 1220 EUR |
NOD2 Rabbit pAb |
|||
| A15992-100ul | Abclonal | 100 ul | 369.6 EUR |
NOD2 Rabbit pAb |
|||
| A15992-200ul | Abclonal | 200 ul | 550.8 EUR |
NOD2 Rabbit pAb |
|||
| A15992-20ul | Abclonal | 20 ul | 219.6 EUR |
NOD2 Rabbit pAb |
|||
| A15992-50ul | Abclonal | 50 ul | 267.6 EUR |
NOD2 Rabbit pAb |
|||
| E2161510 | EnoGene | 100ul | 225 EUR |
|
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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NOD2 Rabbit pAb |
|||
| E2861510 | EnoGene | 100ul | 225 EUR |
|
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
|||
NOD2 Rabbit pAb |
|||
| MBS9142141-002mL | MyBiosource | 0.02mL | 200 EUR |
NOD2 Rabbit pAb |
|||
| MBS9142141-005mL | MyBiosource | 0.05mL | 255 EUR |
NOD2 Rabbit pAb |
|||
| MBS9142141-01mL | MyBiosource | 0.1mL | 345 EUR |
NOD2 Rabbit pAb |
|||
| MBS9142141-02mL | MyBiosource | 0.2mL | 545 EUR |
NOD2 Rabbit pAb |
|||
| MBS9142141-5x02mL | MyBiosource | 5x0.2mL | 2265 EUR |
NOD2 Rabbit pAb |
|||
| A15992 | Abclonal | 500μL | 173.58 EUR |
NOD2 siRNA (Human) |
|||
| MBS8224622-15nmol | MyBiosource | 15nmol | 405 EUR |
NOD2 siRNA (Human) |
|||
| MBS8224622-30nmol | MyBiosource | 30nmol | 565 EUR |
NOD2 siRNA (Human) |
|||
| MBS8224622-5x30nmol | MyBiosource | 5x30nmol | 2450 EUR |
NOD2 antagonist 1 |
|||
| T63088-10mg | TargetMol Chemicals | 10mg | Ask for price |
|
Description: NOD2 antagonist 1 |
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NOD2 antagonist 1 |
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| T63088-1g | TargetMol Chemicals | 1g | Ask for price |
|
Description: NOD2 antagonist 1 |
|||
NOD2 antagonist 1 |
|||
| T63088-1mg | TargetMol Chemicals | 1mg | Ask for price |
|
Description: NOD2 antagonist 1 |
|||
NOD2 antagonist 1 |
|||
| T63088-50mg | TargetMol Chemicals | 50mg | Ask for price |
|
Description: NOD2 antagonist 1 |
|||
NOD2 antagonist 1 |
|||
| T63088-5mg | TargetMol Chemicals | 5mg | Ask for price |
|
Description: NOD2 antagonist 1 |
|||
NOD2 antagonist 1 |
|||
| HY-147506 | MedChemExpress | Get quote | Ask for price |
|
Description: NOD2 antagonist 1 (compound 32) is a potent and selective NOD2 antagonist with an IC50 of 5.23 μM. NOD2 antagonist 1 inhibits Muramyl dipeptide (MDP)-induced IL-8 secretion in THP-1 cells and inhibits MDP-induced IL-6, IL-10, TNF-α release in PBMCs[1]. |
|||
NOD2 Blocking Peptide |
|||
| DF12125-BP | Affbiotech | 1mg | 234 EUR |
NOD2 Blocking Peptide |
|||
| MBS9620830-1mg | MyBiosource | 1mg | 380 EUR |
NOD2 Blocking Peptide |
|||
| MBS9620830-5x1mg | MyBiosource | 5x1mg | 1650 EUR |
NOD2 Polyclonal Antibody |
|||
| E915992 | EnoGene | 100ul | 225 EUR |
|
Description: Available in various conjugation types. |
|||
Polyclonal NOD2 Antibody |
|||
| APR06297G | Leading Biology | 0.1 mg | 790.8 EUR |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NOD2 . This antibody is tested and proven to work in the following applications: |
|||
Polyclonal NOD2 Antibody |
|||
| APR06298G | Leading Biology | 0.1 mg | 790.8 EUR |
|
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NOD2 . This antibody is tested and proven to work in the following applications: |
|||
NOD2 Conjugated Antibody |
|||
| C37460 | SAB | 100ul | 476.4 EUR |
NOD2 Polyclonal Antibody |
|||
| E-AB-91396-120uL | Elabscience Biotech | 120uL | 320 EUR |
|
Description: Unconjugated |
|||
NOD2 Polyclonal Antibody |
|||
| E-AB-91396-200uL | Elabscience Biotech | 200uL | 530 EUR |
|
Description: Unconjugated |
|||
NOD2 Polyclonal Antibody |
|||
| E-AB-91396-60uL | Elabscience Biotech | 60uL | 200 EUR |
|
Description: Unconjugated |
|||
NOD2 Polyclonal Antibody |
|||
| E-AB-91396-each | Elabscience Biotech | each | Ask for price |
|
Description: Unconjugated |
|||
NOD2 Polyclonal Antibody |
|||
| E-AB-13109-120uL | Elabscience Biotech | 120uL | 240 EUR |
|
Description: Unconjugated |
|||
NOD2 Polyclonal Antibody |
|||
| E-AB-13109-200uL | Elabscience Biotech | 200uL | 399 EUR |
|
Description: Unconjugated |
|||
NOD2 Polyclonal Antibody |
|||
| E-AB-13109-20uL | Elabscience Biotech | 20uL | 73 EUR |
|
Description: Unconjugated |
|||
NOD2 Polyclonal Antibody |
|||
| E-AB-13109-60uL | Elabscience Biotech | 60uL | 143 EUR |
|
Description: Unconjugated |
|||
NOD2 Polyclonal Antibody |
|||
| MBS8570672-01mL | MyBiosource | 0.1mL | 305 EUR |
NOD2 Polyclonal Antibody |
|||
| MBS8570672-01mLAF405L | MyBiosource | 0.1mL(AF405L) | 565 EUR |
NOD2 Polyclonal Antibody |
|||
| MBS8570672-01mLAF405S | MyBiosource | 0.1mL(AF405S) | 565 EUR |
NOD2 Polyclonal Antibody |
|||
| MBS8570672-01mLAF610 | MyBiosource | 0.1mL(AF610) | 565 EUR |
NOD2 Polyclonal Antibody |
|||
| MBS8570672-01mLAF635 | MyBiosource | 0.1mL(AF635) | 565 EUR |
NOD2 Polyclonal Antibody |
|||
| MBS2527899-002mL | MyBiosource | 0.02mL | 140 EUR |
NOD2 Polyclonal Antibody |
|||
| MBS2527899-006mL | MyBiosource | 0.06mL | 180 EUR |
NOD2 Polyclonal Antibody |
|||
| MBS2527899-012mL | MyBiosource | 0.12mL | 260 EUR |
NOD2 Polyclonal Antibody |
|||
| MBS2527899-02mL | MyBiosource | 0.2mL | 405 EUR |
NOD2 Polyclonal Antibody |
|||
| MBS2528827-002mL | MyBiosource | 0.02mL | 135 EUR |
NOD2 Polyclonal Antibody |
|||
| MBS2528827-006mL | MyBiosource | 0.06mL | 190 EUR |
NOD2 Polyclonal Antibody |
|||
| MBS2528827-012mL | MyBiosource | 0.12mL | 265 EUR |
NOD2 Polyclonal Antibody |
|||
| MBS2528827-02mL | MyBiosource | 0.2mL | 415 EUR |
NOD2 Polyclonal Antibody |
|||
| MBS2528827-5x02mL | MyBiosource | 5x0.2mL | 1835 EUR |
NOD2 Conjugated Antibody |
|||
| MBS9447900-01mLAF350 | MyBiosource | 0.1mL(AF350) | 480 EUR |
NOD2 Conjugated Antibody |
|||
| MBS9447900-01mLAF405 | MyBiosource | 0.1mL(AF405) | 480 EUR |
NOD2 Conjugated Antibody |
|||
| MBS9447900-01mLAF488 | MyBiosource | 0.1mL(AF488) | 480 EUR |
NOD2 Conjugated Antibody |
|||
| MBS9447900-01mLAF555 | MyBiosource | 0.1mL(AF555) | 480 EUR |
NOD2 Conjugated Antibody |
|||
| MBS9447900-01mLBiotin | MyBiosource | 0.1mL(Biotin) | 480 EUR |
NOD2 Polyclonal Antibody |
|||
| RD76743A-120uL | Reddot Biotech | 120μL | 360 EUR |
|
Description: This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. |
|||
NOD2 Polyclonal Antibody |
|||
| RD76743A-200uL | Reddot Biotech | 200μL | 630 EUR |
|
Description: This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. |
|||
NOD2 Polyclonal Antibody |
|||
| RD76743A-20uL | Reddot Biotech | 20μL | 109.5 EUR |
|
Description: This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. |
|||
NOD2 Polyclonal Antibody |
|||
| RD76743A-60uL | Reddot Biotech | 60μL | 214.5 EUR |
|
Description: This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. |
|||
NOD2 (untagged)-Human nucleotide-binding oligomerization domain containing 2 (NOD2) |
|||
| SC305010 | Origene Technologies GmbH | 10 µg | Ask for price |
Mouse Nod2 ELISA KIT |
|||
| ELI-44123m | Nova Lifetech | 96tests | 736 EUR |
Human NOD2 ELISA KIT |
|||
| EF001273 | Nova Lifetech | 96tests | 566 EUR |
Human NOD2 ELISA KIT |
|||
| ELI-23582h | Nova Lifetech | 96tests | 696 EUR |
NOD2, Human, mAb hNOD2.017 |
|||
| MBS584763-01mg | MyBiosource | 0.1mg | 660 EUR |
NOD2, Human, mAb hNOD2.017 |
|||
| MBS584763-05mg | MyBiosource | 0.5mg | 1695 EUR |
NOD2, Human, mAb hNOD2.017 |
|||
| MBS584763-1mg | MyBiosource | 1mg | 2370 EUR |
NOD2, Human, mAb hNOD2.017 |
|||
| MBS584763-5mg | MyBiosource | 5mg | 7845 EUR |
Bovine NOD2 ELISA KIT |
|||
| ELI-22273b | Nova Lifetech | 96tests | 796 EUR |
NOD2 Antibody (C-term) |
|||
| GWB-949D66 | GenWay Biotech | 0.05 mg | Ask for price |
NOD2 Antibody (C-term) |
|||
| GWB-B15211 | GenWay Biotech | 0.1 mg | Ask for price |
Human NOD2 shRNA Plasmid |
|||
| 20-abx961935 | Abbexa |
|
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Human NOD2 Protein Lysate |
|||
| MBS8416124-002mg | MyBiosource | 0.02mg | 545 EUR |
Human NOD2 Protein Lysate |
|||
| MBS8416124-5x002mg | MyBiosource | 5x0.02mg | 2225 EUR |
TLR2 & NOD2-Based Adjuvant |
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| VAdv-Ly0016 | Creative Biolabs | 5 mg | 4016.4 EUR |
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Description: A TLR2 & NOD2-based vaccine adjuvant. |
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NOD2 Antibody, HRP conjugated |
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| 1-CSB-PA881021LB01HU | Cusabio |
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Description: A polyclonal antibody against NOD2. Recognizes NOD2 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
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NOD2 Antibody, HRP conjugated |
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| MBS7051337-005mg | MyBiosource | 0.05mg | 190 EUR |
NOD2 Antibody, HRP conjugated |
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| MBS7051337-01mg | MyBiosource | 0.1mg | 270 EUR |
NOD2 Antibody, HRP conjugated |
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| MBS7051337-5x01mg | MyBiosource | 5x0.1mg | 1205 EUR |
NOD2 Antibody, FITC conjugated |
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| 1-CSB-PA881021LC01HU | Cusabio |
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Description: A polyclonal antibody against NOD2. Recognizes NOD2 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
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NOD2 Antibody, FITC conjugated |
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| MBS7051338-005mg | MyBiosource | 0.05mg | 190 EUR |
NOD2 Antibody, FITC conjugated |
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| MBS7051338-01mg | MyBiosource | 0.1mg | 270 EUR |
NOD2 Antibody, FITC conjugated |
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| MBS7051338-5x01mg | MyBiosource | 5x0.1mg | 1205 EUR |
OACA10693-50UG - NOD2 Antibody |
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| OACA10693-50UG | Aviva Systems Biology | 50ug | 179 EUR |
CARD15 / NOD2 Immunizing Peptide |
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| MBS426509-01mg | MyBiosource | 0.1mg | 225 EUR |
Nod2 (untagged) - Mouse nucleotide-binding oligomerization domain containing 2 (Nod2), (10ug) |
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| MC223222 | Origene Technologies GmbH | 10 µg | Ask for price |
NOD2 (GFP-tagged) - Human nucleotide-binding oligomerization domain containing 2 (NOD2) |
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| RG215750 | Origene Technologies GmbH | 10 µg | Ask for price |
NOD2 Rabbit Polyclonal Antibody |
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| 54121 | SAB | 100ul | 439 EUR |
NOD2 Antibody, Biotin conjugated |
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| 1-CSB-PA881021LD01HU | Cusabio |
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Description: A polyclonal antibody against NOD2. Recognizes NOD2 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
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Rabbit Polyclonal NOD2 Antibody |
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| TA306091 | Origene Technologies GmbH | 100 µg | Ask for price |
Rabbit Polyclonal NOD2 Antibody |
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| TA306092 | Origene Technologies GmbH | 100 µg | Ask for price |
Rabbit Polyclonal NOD2 Antibody |
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| TA336664 | Origene Technologies GmbH | 100 µl | Ask for price |
OAPB00158-100UG - NOD2 Antibody |
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| OAPB00158-100UG | Aviva Systems Biology | 0.1mg | 389 EUR |
OACA10693-100UG - NOD2 Antibody |
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| OACA10693-100UG | Aviva Systems Biology | 100ug | 319 EUR |
NOD2 Rabbit Polyclonal Antibody |
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| E10G04737 | EnoGene | 100 μl | 275 EUR |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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NOD2 Rabbit Polyclonal Antibody |
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| E10G11622 | EnoGene | 100 μl | 275 EUR |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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NOD2 Antibody, Biotin conjugated |
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| MBS7051339-005mg | MyBiosource | 0.05mg | 190 EUR |
NOD2 Antibody, Biotin conjugated |
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| MBS7051339-01mg | MyBiosource | 0.1mg | 270 EUR |
NOD2 Antibody, Biotin conjugated |
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| MBS7051339-5x01mg | MyBiosource | 5x0.1mg | 1205 EUR |
NOD2 Rabbit Polyclonal Antibody |
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| MBS9465336-005mL | MyBiosource | 0.05mL | 300 EUR |
NOD2 Rabbit Polyclonal Antibody |
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| MBS9465336-01mL | MyBiosource | 0.1mL | 390 EUR |
NOD2 Rabbit Polyclonal Antibody |
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| MBS9465336-5x01mL | MyBiosource | 5x0.1mL | 1610 EUR |
Nod2 (Myc-DDK-tagged) - Mouse nucleotide-binding oligomerization domain containing 2 (Nod2) |
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| MR227102 | Origene Technologies GmbH | 10 µg | Ask for price |
Nod2 (GFP-tagged) - Mouse nucleotide-binding oligomerization domain containing 2 (Nod2), (10ug) |
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| MG227102 | Origene Technologies GmbH | 10 µg | Ask for price |
NOD2 (Myc-DDK-tagged)-Human nucleotide-binding oligomerization domain containing 2 (NOD2) |
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| RC215750 | Origene Technologies GmbH | 10 µg | Ask for price |
Nod2 ORF Vector (Rat) (pORF) |
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| ORF071395 | ABM | 1.0 ug DNA | 607.2 EUR |
NOD2 ORF Vector (Human) (pORF) |
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| ORF026166 | ABM | 1.0 ug DNA | 486 EUR |
Nod2 ORF Vector (Mouse) (pORF) |
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| ORF051499 | ABM | 1.0 ug DNA | 607.2 EUR |
Human NOD2 knockout cell line |
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| ABC-KH10202 | AcceGen | 1 vial | Ask for price |
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Description: Human NOD2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
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Human NOD2 knockdown cell line |
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| ABC-KD10202 | AcceGen | 1 vial | Ask for price |
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Description: Human NOD2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
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Human NOD2 Protein Lysate 20ug |
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| IHUNOD2PLLY20UG | Innovative research | each | 361 EUR |
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Description: Human NOD2 Protein Lysate 20ug |
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NOD2 ELISA Kit (Human) (OKCD02031) |
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| OKCD02031 | Aviva Systems Biology | 96 Wells | 997.2 EUR |
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Description: Description of target: Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.055 ng/mL |
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NOD2 ELISA Kit (Mouse) (OKCA01740) |
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| OKCA01740 | Aviva Systems Biology | 96 Wells | 1015.2 EUR |
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Description: Description of target: Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response (PubMed:22607974). Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages (PubMed:18511561).;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sanadwich ELISA;Sensitivity: 3.9 pg/mL |
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NOD2 ELISA Kit (Human) (OKCA02128) |
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| OKCA02128 | Aviva Systems Biology | 96 Wells | 999.6 EUR |
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Description: Description of target: Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.25 pg/mL |
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NOD2 ELISA Kit (Human) (OKAN06319) |
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| OKAN06319 | Aviva Systems Biology | 96 Wells | 950.4 EUR |
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Description: Description of target: This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.055 ng/mL |
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Nod2 (untagged ORF) - Rat nucleotide-binding oligomerization domain containing 2 (Nod2), (10 ug) |
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| RN215677 | Origene Technologies GmbH | 10 µg | Ask for price |
Polyclonal Antibody to NOD2 (Card15) |
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| MBS668737-005mL | MyBiosource | 0.05mL | 360 EUR |
Polyclonal Antibody to NOD2 (Card15) |
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| MBS668737-5x005mL | MyBiosource | 5x0.05mL | 1600 EUR |
OCOA08638-20UG - NOD2 Protein Lysate |
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| OCOA08638-20UG | Aviva Systems Biology | 20ug | 269 EUR |
Anti-CARD15 / NOD2 (Internal) antibody |
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| STJ70992 | St John's Laboratory | 100 µg | 430.8 EUR |
NOD2 (untagged) - Human nucleotide-binding oligomerization domain containing 2 (NOD2), transcript variant 2 |
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| SC337777 | Origene Technologies GmbH | 10 µg | Ask for price |
CARD15 (NOD2) (NM_022162) Human Over-expression Lysate |
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| LS064127 | BosterBio | 100ug | 960 EUR |
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Description: Transient overexpression lysate of nucleotide-binding oligomerization domain containing 2 (NOD2) |
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Nod2 (Myc-DDK-tagged ORF) - Rat nucleotide-binding oligomerization domain containing 2 (Nod2), (10 ug) |
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| RR215677 | Origene Technologies GmbH | 10 µg | Ask for price |
OKCD02031-96W - NOD2 ELISA Kit (Human) |
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| OKCD02031-96W | Aviva Systems Biology | 96Wells | 675 EUR |
Nod2 sgRNA CRISPR Lentivector set (Rat) |
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| K6718501 | ABM | 3 x 1.0 ug | 406.8 EUR |
Lenti ORF clone of Nod2 (mGFP-tagged) - Mouse nucleotide-binding oligomerization domain containing 2 (Nod2) |
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| MR227102L4 | Origene Technologies GmbH | 10 µg | Ask for price |
Rabbit Polyclonal to Human NOD2 / CARD15 |
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| MBS242180-005mg | MyBiosource | 0.05mg | 715 EUR |
Rabbit Polyclonal to Human NOD2 / CARD15 |
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| MBS242180-5x005mg | MyBiosource | 5x0.05mg | 3035 EUR |
Nod2 sgRNA CRISPR Lentivector set (Mouse) |
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| K4411601 | ABM | 3 x 1.0 ug | 406.8 EUR |
NOD2 sgRNA CRISPR Lentivector set (Human) |
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| K1438601 | ABM | 3 x 1.0 ug | 406.8 EUR |
Lenti-ORF clone of NOD2 (mGFP-tagged)-Human nucleotide-binding oligomerization domain containing 2 (NOD2) |
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| RC215750L2 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti-ORF clone of NOD2 (mGFP-tagged)-Human nucleotide-binding oligomerization domain containing 2 (NOD2) |
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| RC215750L4 | Origene Technologies GmbH | 10 µg | Ask for price |
Goat anti-CARD15 / NOD2 (Internal) Antibody |
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| dAP-0930 | Angio Proteomie | 50ug | 264.6 EUR |
Goat anti-CARD15/NOD2 (Internal) Antibody |
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| MBS420357-01mg | MyBiosource | 0.1mg | 400 EUR |
Goat anti-CARD15/NOD2 (Internal) Antibody |
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| MBS420357-5x01mg | MyBiosource | 5x0.1mg | 1660 EUR |
NOD2 (myc-DDK-tagged) - Human nucleotide-binding oligomerization domain containing 2 (NOD2), transcript variant 2 |
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| RC239883 | Origene Technologies GmbH | 10 µg | Ask for price |
Polyclonal NOD2 / CARD15 Antibody (N-Terminus) |
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| APR02524G | Leading Biology | 0.05mg | 580.8 EUR |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NOD2 / CARD15 (N-Terminus). This antibody is tested and proven to work in the following applications: |
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Polyclonal NOD2 / CARD15 Antibody (C-Terminus) |
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| APR02525G | Leading Biology | 0.05mg | 580.8 EUR |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NOD2 / CARD15 (C-Terminus). This antibody is tested and proven to work in the following applications: |
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Data evaluation was performed utilizing Statistical Package for Social Sciences model 20.Left aspect predominated with 88 (63.7%) and extension kind was frequent in 135 (97.8%). Thirteen (9.4%) sufferers had been initially managed by conventional bonesetters. A complete of 138 kids underwent operative fixation with imply age of seven.47 years and gender ratio of two:1 boy to woman.
Fall from cliff, ladders and rooftops had been the prevailing explanation for harm 73 (52.8%). Average time between harm and surgical procedure was 5.2 days. Closed discount was performed in 100 (72.4%) sufferers whereas open discount was crucial in 38 (27.5%) sufferers.Closed extension kind pediatric supracondylar fracture was frequent in this examine. Fall from cliff, rooftop and ladder are the most important explanation for fracture. Delayed presentation and preliminary administration of the fracture by the standard bonesetters makes supracondylar fracture tougher in useful resource restricted setting like ours.
