Radium 223 combined with new hormone therapies for the treatment of castrate-resistant metastatic prostate cancer: scientific evidence and sharing of our experience.

Radium 223 combined with new hormone therapies for the treatment of castrate-resistant metastatic prostate cancer: scientific evidence and sharing of our experience.
Presentation of the attention-grabbing case of a affected person affected by castrate-resistant prostate most cancers (CRPC) with bone metastasis, who obtained concomitant treatment with abiraterone acetate (AA) and radium-223. The affected person skilled important scientific enchancment in his high quality of life and ache aid after starting the aforementioned treatment, with out being affected by opposed toxicities.
Currently, the appropriate choice of sufferers to obtain radium-223 treatment remains to be a scientific problem in the case of CRPC with metastasis. In this text, we talk about the future prospects of this treatment, reviewing present evidence about concomitant therapies with radium-223 and its current state, primarily based upon the current suggestions from the Pharmacovigilance Risk Assessment Committee (PRAC), and the knowledge offered in the ERA-223 examine.
Based on our scientific expertise, we offer sensible orientation for the integration of this radiopharmaceutical in the therapeutic plan for this group of sufferers. We conclude, regardless of some of the constructive outcomes and our wonderful expertise, that it will be clever to attend for the outcomes of the scientific trials which are finding out the security and advantages of the combined use of radium-223 with new hormone therapies.
Bearing in thoughts that to this point, the solely revealed large-scale randomised trial that investigated the mixture of AR-axis-targeted remedy with Ra-223 is unfavourable, the harms of the mixture outweighed any advantages in ERA-223. Nonetheless, with a purpose to advocate whether or not or not this treatment must be used, it’s important to outline the affected person profile that would profit from this therapeutic possibility.
Radium 223 combined with new hormone therapies for the treatment of castrate-resistant metastatic prostate cancer: scientific evidence and sharing of our experience.
Radium 223 combined with new hormone therapies for the treatment of castrate-resistant metastatic prostate most cancers: scientific evidence and sharing of our expertise.

Patterns of Metastasis in Merkel Cell Carcinoma.

Patterns of Metastasis in Merkel Cell Carcinoma.

Merkel cell carcinoma (MCC) is a cutaneous neuroendocrine malignancy with a propensity for regional and distant unfold. Because of the relative infrequency of this illness, the patterns of metastasis in MCC are understudied.Patients with American Joint Committee on Cancer (eighth version) stage I-IV MCC handled at our establishment were recognized (1/1/2008-2/28/2018). The first web site of metastasis was categorized as regional [regional lymph node (LN) basin, in-transit] or distant. Distant metastasis-free (DMFS) and MCC-specific (MSS) survival have been estimated.

Results

Of 133 sufferers, 64 (48%) had stage I, 13 (10%) stage II, 48 (36%) stage III, and eight (6%) stage IV illness at presentation. The median follow-up time in sufferers who remained alive was 36 (interquartile vary 20-66) months. Regional or distant metastases developed in 78 (59%) sufferers. The first web site was regional in 87%, together with 73% with remoted LN involvement, and distant in 13%. Thirty-seven (28%) sufferers ultimately developed distant illness, which mostly concerned the belly viscera (51%) and distant LNs (46%) first.

The lung (0%) and mind (3%) have been not often the primary distant websites. Stage III MCC at presentation was considerably related to worse DMFS (hazard ratio 4.87, P = 0.001) and stage IV illness with worse MSS (hazard ratio 6.30, P = 0.002).Regional LN metastasis is the commonest first metastatic occasion in MCC, confirming the significance of nodal analysis. Distant illness unfold seems to have a predilection for sure websites. Understanding these patterns might assist to information surveillance methods.

Patterns of Metastasis in Merkel Cell Carcinoma.
Patterns of Metastasis in Merkel Cell Carcinoma.

Coronavirus Disease-19 (COVID-19) related to extreme acute pancreatitis: Case report on three relations.

Abdominal ache is one of the recognized signs related to coronavirus illness 2019. Little is thought in regards to the growth of acute pancreatitis as a complication of extreme acute respiratory syndrome coronavirus 2 an infection. This case report describes the presentation of acute pancreatitis in two of three relations with extreme COVID-19 an infection.

Data have been collected from three relations admitted with COVID-19 to the intensive care unit in March 2020. This research was reviewed and accepted by the native information and ethics committee (31-1521-253).

Nod2 antibody

10R-6553 Fitzgerald 100 ug 522 EUR
Description: Rat monoclonal Nod2 antibody

NOD2 Antibody

24158-100ul SAB 100ul 468 EUR

NOD2 Antibody

24159-100ul SAB 100ul 468 EUR

NOD2 Antibody

2511-002mg ProSci 0.02 mg 206.18 EUR
Description: NOD2 Antibody: Apaf-1 and NOD1 are members of a new family, which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2. NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-κB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease that is a main type of chronic inflammatory bowel disease.

NOD2 Antibody

2511-01mg ProSci 0.1 mg 523.7 EUR
Description: NOD2 Antibody: Apaf-1 and NOD1 are members of a new family, which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2. NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-κB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease that is a main type of chronic inflammatory bowel disease.

NOD2 Antibody

2513-002mg ProSci 0.02 mg 206.18 EUR
Description: NOD2 Antibody: Apaf-1 and NOD1 are members of a new family, which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2. NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-κB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease that is a main type of chronic inflammatory bowel disease.

NOD2 Antibody

2513-01mg ProSci 0.1 mg 523.7 EUR
Description: NOD2 Antibody: Apaf-1 and NOD1 are members of a new family, which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2. NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-κB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease that is a main type of chronic inflammatory bowel disease.

NOD2 Antibody

37460-100ul SAB 100ul 302.4 EUR

NOD2 antibody

70R-18913 Fitzgerald 50 ul 522 EUR
Description: Rabbit polyclonal NOD2 antibody

NOD2 Antibody

DF12125 Affbiotech 200ul 420 EUR

NOD2 Antibody

1-CSB-PA876985 Cusabio
  • 380.40 EUR
  • 292.80 EUR
  • 100ul
  • 50ul
Description: A polyclonal antibody against NOD2. Recognizes NOD2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100

NOD2 Antibody

1-CSB-PA881021LA01HU Cusabio
  • 380.40 EUR
  • 402.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against NOD2. Recognizes NOD2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

NOD2 Antibody

1-CSB-PA015915GA01HU Cusabio
  • 716.40 EUR
  • 399.60 EUR
  • 150ul
  • 50ul
Description: A polyclonal antibody against NOD2. Recognizes NOD2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB

NOD2 Antibody

1-CSB-PA446192 Cusabio
  • 380.40 EUR
  • 292.80 EUR
  • 100ul
  • 50ul
Description: A polyclonal antibody against NOD2. Recognizes NOD2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200

NOD2 Antibody

R34436-100UG NSJ Bioreagents 100 ug 339.15 EUR
Description: Additional name(s) for this target protein: Nucleotide-binding oligomerization domain-containing protein 2, caspase recruitment domain family, member 15; CARD15

NOD2 Rabbit pAb

A15992-100ul Abclonal 100 ul 369.6 EUR

NOD2 Rabbit pAb

A15992-200ul Abclonal 200 ul 550.8 EUR

NOD2 Rabbit pAb

A15992-20ul Abclonal 20 ul 219.6 EUR

NOD2 Rabbit pAb

A15992-50ul Abclonal 50 ul 267.6 EUR

NOD2 Blocking Peptide

DF12125-BP Affbiotech 1mg 234 EUR

Polyclonal NOD2 Antibody

APR06297G Leading Biology 0.1 mg 790.8 EUR
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NOD2 . This antibody is tested and proven to work in the following applications:

Polyclonal NOD2 Antibody

APR06298G Leading Biology 0.1 mg 790.8 EUR
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NOD2 . This antibody is tested and proven to work in the following applications:

NOD2 Conjugated Antibody

C37460 SAB 100ul 476.4 EUR

NOD2 ELISA KIT|Human

EF001273 Lifescience Market 96 Tests 826.8 EUR

Mouse Nod2 ELISA KIT

ELI-44123m Lifescience Market 96 Tests 1038 EUR

Human NOD2 ELISA KIT

ELI-23582h Lifescience Market 96 Tests 988.8 EUR

Bovine NOD2 ELISA KIT

ELI-22273b Lifescience Market 96 Tests 1113.6 EUR

Human NOD2 shRNA Plasmid

20-abx961935 Abbexa
  • 961.20 EUR
  • 1345.20 EUR
  • 150 µg
  • 300 µg

TLR2 & NOD2-Based Adjuvant

VAdv-Ly0016 Creative Biolabs 5 mg 4016.4 EUR
Description: A TLR2 & NOD2-based vaccine adjuvant.

NOD2 Antibody, HRP conjugated

1-CSB-PA881021LB01HU Cusabio
  • 380.40 EUR
  • 402.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against NOD2. Recognizes NOD2 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

NOD2 Antibody, FITC conjugated

1-CSB-PA881021LC01HU Cusabio
  • 380.40 EUR
  • 402.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against NOD2. Recognizes NOD2 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

NOD2 Antibody, Biotin conjugated

1-CSB-PA881021LD01HU Cusabio
  • 380.40 EUR
  • 402.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against NOD2. Recognizes NOD2 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Nod2 ORF Vector (Rat) (pORF)

ORF071395 ABM 1.0 ug DNA 607.2 EUR

NOD2 ORF Vector (Human) (pORF)

ORF026166 ABM 1.0 ug DNA 486 EUR

Nod2 ORF Vector (Mouse) (pORF)

ORF051499 ABM 1.0 ug DNA 607.2 EUR

NOD2 ELISA Kit (Human) (OKAN06319)

OKAN06319 Aviva Systems Biology 96 Wells 950.4 EUR
Description: Description of target: This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.055 ng/mL

NOD2 ELISA Kit (Mouse) (OKCA01740)

OKCA01740 Aviva Systems Biology 96 Wells 1015.2 EUR
Description: Description of target: Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response (PubMed:22607974). Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages (PubMed:18511561).;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sanadwich ELISA;Sensitivity: 3.9 pg/mL

NOD2 ELISA Kit (Human) (OKCA02128)

OKCA02128 Aviva Systems Biology 96 Wells 999.6 EUR
Description: Description of target: Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 6.25 pg/mL

NOD2 ELISA Kit (Human) (OKCD02031)

OKCD02031 Aviva Systems Biology 96 Wells 997.2 EUR
Description: Description of target: Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.055 ng/mL

Anti-CARD15 / NOD2 (Internal) antibody

STJ70992 St John's Laboratory 100 µg 430.8 EUR

h NOD2 inducible lentiviral particles

LVP627 GenTarget 1x107 IFU/ml x 200ul 541.2 EUR
Description: Pre-made over-expression lentivirus for expressing human target: NOD2 (nucleotide-binding oligomerization domain containing 2), [alternative names: ACUG; BLAU; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2B; PSORAS1]. The sub-cloned codon sequence is identical (100% match) to CDS region in NCBI ID: NM_022162.1. It also contains a RFP-Blasticidin dual selection marker.

Nod2 sgRNA CRISPR Lentivector set (Rat)

K6718501 ABM 3 x 1.0 ug 406.8 EUR

NOD2 sgRNA CRISPR Lentivector set (Human)

K1438601 ABM 3 x 1.0 ug 406.8 EUR

Nod2 sgRNA CRISPR Lentivector set (Mouse)

K4411601 ABM 3 x 1.0 ug 406.8 EUR

Nod2 3'UTR GFP Stable Cell Line

TU164191 ABM 1.0 ml Ask for price

NOD2 3'UTR GFP Stable Cell Line

TU065801 ABM 1.0 ml 1636.8 EUR

Nod2 3'UTR GFP Stable Cell Line

TU264065 ABM 1.0 ml Ask for price

Polyclonal NOD2 / CARD15 Antibody (N-Terminus)

APR02524G Leading Biology 0.05mg 580.8 EUR
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NOD2 / CARD15 (N-Terminus). This antibody is tested and proven to work in the following applications:

Polyclonal NOD2 / CARD15 Antibody (C-Terminus)

APR02525G Leading Biology 0.05mg 580.8 EUR
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NOD2 / CARD15 (C-Terminus). This antibody is tested and proven to work in the following applications:

NOD2 Protein Vector (Rat) (pPM-C-HA)

PV285580 ABM 500 ng 1399.2 EUR

NOD2 Protein Vector (Rat) (pPB-C-His)

PV285578 ABM 500 ng 1399.2 EUR

NOD2 Protein Vector (Rat) (pPB-N-His)

PV285579 ABM 500 ng 1399.2 EUR

NOD2 Protein Vector (Rat) (pPM-C-His)

PV285581 ABM 500 ng 1399.2 EUR

NOD2 Protein Vector (Human) (pPM-C-HA)

PV104664 ABM 500 ng 973.2 EUR

NOD2 Protein Vector (Mouse) (pPM-C-HA)

PV205996 ABM 500 ng 1278 EUR

NOD2 Protein Vector (Human) (pPB-C-His)

PV104662 ABM 500 ng 973.2 EUR

NOD2 Protein Vector (Human) (pPB-N-His)

PV104663 ABM 500 ng 973.2 EUR

NOD2 Protein Vector (Human) (pPM-C-His)

PV104665 ABM 500 ng 973.2 EUR

NOD2 Protein Vector (Mouse) (pPB-C-His)

PV205994 ABM 500 ng 1278 EUR

NOD2 Protein Vector (Mouse) (pPB-N-His)

PV205995 ABM 500 ng 1278 EUR

NOD2 Protein Vector (Mouse) (pPM-C-His)

PV205997 ABM 500 ng 1278 EUR

Nod2 3'UTR Luciferase Stable Cell Line

TU114191 ABM 1.0 ml Ask for price

NOD2 3'UTR Luciferase Stable Cell Line

TU015801 ABM 1.0 ml 1636.8 EUR

Nod2 3'UTR Luciferase Stable Cell Line

TU214065 ABM 1.0 ml Ask for price

Nod2 sgRNA CRISPR Lentivector (Rat) (Target 1)

K6718502 ABM 1.0 ug DNA 184.8 EUR

Nod2 sgRNA CRISPR Lentivector (Rat) (Target 2)

K6718503 ABM 1.0 ug DNA 184.8 EUR

Nod2 sgRNA CRISPR Lentivector (Rat) (Target 3)

K6718504 ABM 1.0 ug DNA 184.8 EUR

NOD2 sgRNA CRISPR Lentivector (Human) (Target 1)

K1438602 ABM 1.0 ug DNA 184.8 EUR

NOD2 sgRNA CRISPR Lentivector (Human) (Target 2)

K1438603 ABM 1.0 ug DNA 184.8 EUR

NOD2 sgRNA CRISPR Lentivector (Human) (Target 3)

K1438604 ABM 1.0 ug DNA 184.8 EUR

Nod2 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4411602 ABM 1.0 ug DNA 184.8 EUR

Nod2 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4411603 ABM 1.0 ug DNA 184.8 EUR

Nod2 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4411604 ABM 1.0 ug DNA 184.8 EUR

NOD2 Chemi-Luminescent ELISA Kit (Human) (OKCD03832)

OKCD03832 Aviva Systems Biology 96 Wells 1185.6 EUR
Description: Description of target: Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages .;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.0412 ng/mL

Polyclonal Goat Anti-CARD15 / NOD2 (Internal) Antibody

APG00059G Leading Biology 0.1mg 580.8 EUR
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-CARD15 / NOD2 (Internal) . This antibody is tested and proven to work in the following applications:

NOD2 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

LV645601 ABM 1.0 ug DNA 1626 EUR

NOD2 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

LV645605 ABM 1.0 ug DNA 1626 EUR

NOD2 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

LV645606 ABM 1.0 ug DNA 1626 EUR

Nucleotide Binding Oligomerization Domain Containing 2 (NOD2) Antibody

abx235781-100ug Abbexa 100 ug 661.2 EUR

Nucleotide Binding Oligomerization Domain Containing 2 (NOD2) Antibody

20-abx114240 Abbexa
  • 878.40 EUR
  • 477.60 EUR
  • 150 ul
  • 50 ul

Nucleotide Binding Oligomerization Domain Containing 2 (NOD2) Antibody

20-abx302321 Abbexa
  • 493.20 EUR
  • 2214.00 EUR
  • 718.80 EUR
  • 218.40 EUR
  • 360.00 EUR
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Nod2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

K6718505 ABM 3 x 1.0 ug 451.2 EUR

NOD2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K1438605 ABM 3 x 1.0 ug 451.2 EUR

Nod2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K4411605 ABM 3 x 1.0 ug 451.2 EUR

Nucleotide Binding Oligomerization Domain Containing 2 (NOD2) Antibody (HRP)

20-abx316579 Abbexa
  • 493.20 EUR
  • 2214.00 EUR
  • 718.80 EUR
  • 218.40 EUR
  • 360.00 EUR
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Nucleotide Binding Oligomerization Domain Containing 2 (NOD2) Antibody (FITC)

20-abx316580 Abbexa
  • 493.20 EUR
  • 2214.00 EUR
  • 718.80 EUR
  • 218.40 EUR
  • 360.00 EUR
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Nucleotide Binding Oligomerization Domain Containing 2 (NOD2) Antibody (Biotin)

20-abx316581 Abbexa
  • 493.20 EUR
  • 2214.00 EUR
  • 718.80 EUR
  • 218.40 EUR
  • 360.00 EUR
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) Antibody

20-abx211027 Abbexa
  • 493.20 EUR
  • 360.00 EUR
  • 100 ul
  • 50 ul

Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) Antibody

20-abx339338 Abbexa
  • 493.20 EUR
  • 360.00 EUR
  • 100 ul
  • 50 ul

Nod2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

K6718506 ABM 1.0 ug DNA 200.4 EUR

Nod2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)

K6718507 ABM 1.0 ug DNA 200.4 EUR

Nod2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)

K6718508 ABM 1.0 ug DNA 200.4 EUR

NOD2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K1438606 ABM 1.0 ug DNA 200.4 EUR

NOD2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K1438607 ABM 1.0 ug DNA 200.4 EUR

NOD2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K1438608 ABM 1.0 ug DNA 200.4 EUR

Nod2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K4411606 ABM 1.0 ug DNA 200.4 EUR

Nod2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K4411607 ABM 1.0 ug DNA 200.4 EUR

Nod2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K4411608 ABM 1.0 ug DNA 200.4 EUR

NOD2 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV645602 ABM 1.0 ug DNA 1626 EUR

NOD2 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV645603 ABM 1.0 ug DNA 1695.6 EUR

NOD2 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV645604 ABM 1.0 ug DNA 1695.6 EUR

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) CLIA Kit

20-abx190892 Abbexa
  • 9493.20 EUR
  • 5058.00 EUR
  • 1167.60 EUR
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2)CLIA Kit

SCK295Hu-10x96wellstestplate Cloud-Clone 10x96-wells test plate 6777.36 EUR
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) in Tissue homogenates, cell lysates and other biological fluids.

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2)CLIA Kit

SCK295Hu-1x48wellstestplate Cloud-Clone 1x48-wells test plate 663.31 EUR
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) in Tissue homogenates, cell lysates and other biological fluids.

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2)CLIA Kit

SCK295Hu-1x96wellstestplate Cloud-Clone 1x96-wells test plate 896.16 EUR
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) in Tissue homogenates, cell lysates and other biological fluids.

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2)CLIA Kit

SCK295Hu-5x96wellstestplate Cloud-Clone 5x96-wells test plate 3672.72 EUR
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) in Tissue homogenates, cell lysates and other biological fluids.

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) CLIA Kit

4-SCK295Hu Cloud-Clone
  • 6837.60 EUR
  • 3673.20 EUR
  • 896.40 EUR
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2)Tissue homogenates, cell lysates and other biological fluids

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) ELISA Kit

20-abx258642 Abbexa
  • 8853.60 EUR
  • 4719.60 EUR
  • 1093.20 EUR
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) ELISA Kit

SEK295Hu-10x96wellstestplate Cloud-Clone 10x96-wells test plate 5677.8 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) in tissue homogenates, cell lysates and other biological fluids.

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) ELISA Kit

SEK295Hu-1x48wellstestplate Cloud-Clone 1x48-wells test plate 572.76 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) in tissue homogenates, cell lysates and other biological fluids.

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) ELISA Kit

SEK295Hu-1x96wellstestplate Cloud-Clone 1x96-wells test plate 766.8 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) in tissue homogenates, cell lysates and other biological fluids.

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) ELISA Kit

SEK295Hu-5x96wellstestplate Cloud-Clone 5x96-wells test plate 3090.6 EUR
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) in tissue homogenates, cell lysates and other biological fluids.

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) ELISA Kit

4-SEK295Hu Cloud-Clone
  • 5738.40 EUR
  • 3031.20 EUR
  • 768.00 EUR
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Nucleotide Binding Oligomerization Domain Containing Protein 2 (NOD2) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Nucleotide Binding Oligomerization Domain Containing Protein 2 ELISA Kit (NOD2)

RK01942 Abclonal 96 Tests 625.2 EUR

Human Nucleotide-binding oligomerization domain-containing protein 2(NOD2) ELISA kit

CSB-EL015915HU-24T Cusabio 1 plate of 24 wells 198 EUR
Description: Quantitativesandwich ELISA kit for measuring Human Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) in samples from serum, plasma, asciticfluid, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Nucleotide-binding oligomerization domain-containing protein 2(NOD2) ELISA kit

1-CSB-EL015915HU Cusabio
  • 964.80 EUR
  • 6118.80 EUR
  • 3244.80 EUR
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Nucleotide-binding oligomerization domain-containing protein 2(NOD2) in samples from serum, plasma, asciticfluid, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

ELISA kit for Human NOD2 (Nucleotide Binding Oligomerization Domain Containing Protein 2)

ELK5352 ELK Biotech 1 plate of 96 wells 518.4 EUR
Description: A sandwich ELISA kit for detection of Nucleotide Binding Oligomerization Domain Containing Protein 2 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

anti-NOD2

YF-PA27607 Abfrontier 50 ug 435.6 EUR
Description: Mouse polyclonal to NOD2

Anti-NOD2 antibody

PAab05781 Lifescience Market 100 ug 494.4 EUR

Anti-NOD2 antibody

STJ118451 St John's Laboratory 100 µl 332.4 EUR

Anti-NOD2 (Card15) Antibody

A00087 BosterBio 50 ul 476.4 EUR
Description: Rabbit Polyclonal NOD2 (Card15) Antibody. Validated in IP, IHC, WB and tested in Human.

Nod3l/ Rat Nod3l ELISA Kit

ELI-11062r Lifescience Market 96 Tests 1063.2 EUR

pECMV-Nod2-m-FLAG Plasmid

PVT15371 Lifescience Market 2 ug 390 EUR

NOD1 siRNA

20-abx926109 Abbexa
  • 661.20 EUR
  • 878.40 EUR
  • 15 nmol
  • 30 nmol

NOD1 siRNA

20-abx926110 Abbexa
  • 661.20 EUR
  • 878.40 EUR
  • 15 nmol
  • 30 nmol

NOD1 Peptide

42-460P ProSci 0.1 mg 405.6 EUR
Description: (CT) NOD1 Peptide

NOD1 Rabbit pAb

A1246-100ul Abclonal 100 ul 369.6 EUR

NOD1 Rabbit pAb

A1246-200ul Abclonal 200 ul 550.8 EUR

NOD1 Rabbit pAb

A1246-20ul Abclonal 20 ul 219.6 EUR

NOD1 Rabbit pAb

A1246-50ul Abclonal 50 ul 267.6 EUR

NOD1 Peptide

5947P ProSci 0.05 mg 197.7 EUR
Description: (CT) NOD1 peptide

NOD3 Peptide

5949P ProSci 0.05 mg 197.7 EUR
Description: (IN) NOD3 peptide

NOD4 Peptide

5951P ProSci 0.05 mg 197.7 EUR
Description: (NT) NOD4 peptide

NOD5 Peptide

5953P ProSci 0.05 mg 197.7 EUR
Description: (NT) NOD5 peptide

NOD6 Peptide

5955P ProSci 0.05 mg 197.7 EUR
Description: (NT) NOD6 peptide

NOD1 Antibody

25174-100ul SAB 100ul 468 EUR

NOD3 Antibody

25175-100ul SAB 100ul 468 EUR

NOD4 Antibody

25176-100ul SAB 100ul 468 EUR

NOD5 Antibody

25177-100ul SAB 100ul 468 EUR

NOD6 Antibody

25178-100ul SAB 100ul 468 EUR

Nod1 antibody

22788-100ul SAB 100ul 468 EUR

NOD1 Antibody

5947-002mg ProSci 0.02 mg 206.18 EUR
Description: NOD1 Antibody: NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD1 contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and ten tandem leucine-rich repeats (LRRs) in its C-terminus. The CARD is involved in apoptotic signaling, and NOD1 activates caspase-9 and NF-κB. LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.

NOD1 Antibody

5947-01mg ProSci 0.1 mg 523.7 EUR
Description: NOD1 Antibody: NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD1 contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and ten tandem leucine-rich repeats (LRRs) in its C-terminus. The CARD is involved in apoptotic signaling, and NOD1 activates caspase-9 and NF-κB. LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.

NOD3 Antibody

5949-002mg ProSci 0.02 mg 206.18 EUR
Description: NOD3 Antibody: NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells. NOD3 inhibits NF-kappaB, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells.

NOD3 Antibody

5949-01mg ProSci 0.1 mg 523.7 EUR
Description: NOD3 Antibody: NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells. NOD3 inhibits NF-kappaB, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells.

NOD4 Antibody

5951-002mg ProSci 0.02 mg 206.18 EUR
Description: NOD4 Antibody: NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-κB and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.

NOD4 Antibody

5951-01mg ProSci 0.1 mg 523.7 EUR
Description: NOD4 Antibody: NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-κB and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.

NOD5 Antibody

5953-002mg ProSci 0.02 mg 206.18 EUR
Description: NOD5 Antibody: NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-κB and JNK pathways by inducing reactive oxygen species production.

NOD5 Antibody

5953-01mg ProSci 0.1 mg 523.7 EUR
Description: NOD5 Antibody: NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-κB and JNK pathways by inducing reactive oxygen species production.

NOD6 Antibody

5955-002mg ProSci 0.02 mg 206.18 EUR
Description: NOD6 Antibody: NOD6, also known as NALP9, is a member of the NALP family, a group of proteins that typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD) and are involved in inflammation and innate immune defense. The bovine NOD6, which has 76% homology to its human counterpart, has been suggested to be an oocyte marker gene. In adult tissues, NALP9 mRNA is expressed exclusively in ovary and testis.

Two of the three relations have been recognized with acute pancreatitis related to SARS-CoV-2. Other causes of acute pancreatitis have been excluded for each sufferers (together with alcohol, biliary obstruction/gall stones, medication, trauma, hypertriglyceridemia, hypercalcemia, and hypotension).These circumstances spotlight acute pancreatitis as a complication related to COVID-19 and underlines the significance of measuring pancreas-specific plasma amylase in sufferers with COVID-19 and belly ache.